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The Board Trustees of the University of Illinois Urbana-Champaign

Archive-It Partner Since: Jul, 2015

Organization Type: Colleges & Universities

Organization URL: http://illinois.edu/   

Page 1 of 1 (4 Total Results)

Title: Illinois Validates Saliva-Based test for COVID-19

URL: https://blogs.illinois.edu/view/6367/1795135071/

Collection: COVID-19 Response at the University of Illinois

Description: News article reporting on the validation of saliva-based testing for COVID-19 in Illinois.

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Subject:   Health Medical tests (Diagnosis),  PCR (biochemistry) ,  COVID-19 (Disease)

Title: Martin Burke, Paul Hergenrother, COVID-19 Saliva Test in National Spotlight

URL: https://chemistry.illinois.edu/news/2020-08-28/martin-burke-paul-hergenrother-covid-19-saliva-test-national-spotlight/

Collection: COVID-19 Response at the University of Illinois

Description: Webpage sharing a news article about two University of Illinois at Urbana-Champaign Chemistry professors who's COVID019 saliva test was receiving national attention.

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Subject:   Medical tests (Diagnosis) Health,  PCR (biochemistry) ,  COVID-19 (Disease)

Title: Saliva-Based Molecular Testing for SARS-CoV-2 that Bypasses RNA Extraction

URL: https://www.biorxiv.org/content/10.1101/2020.06.18.159434v1.full.pdf/

Collection: COVID-19 Response at the University of Illinois

Description: Preprint article. Abstract: Convenient, repeatable, large-scale molecular testing for SARS-CoV-2 would be a key weapon to help control the COVID-19 pandemic. Unfortunately, standard SARS-CoV-2 testing protocols are invasive and rely on numerous items that can be subject to supply chain bottlenecks, and as such are not suitable for frequent repeat testing. Specifically, personal protective equipment (PPE), nasopharyngeal (NP) swabs, the associated viral transport media (VTM), and kits for RNA isolation and purification have all been in short supply at various times during the COVID-19 pandemic. Moreover, SARS-CoV-2 is spread through droplets and aerosols transmitted through person-to-person contact, and thus saliva may be a relevant medium for diagnosing SARSCoV-2 infection status. Here we describe a saliva-based testing method that bypasses the need for RNA isolation/purification. In experiments with inactivated SARS-CoV-2 virus spiked into saliva, this method has a limit of detection of 500-1000 viral particles per mL, rivalling the standard NP swab method, and initial studies also show excellent performance with 100 clinical samples. This saliva-based process is operationally simple, utilizes readily available materials, and can be easily implemented by existing testing sites, thus allowing for high-throughput, rapid, and repeat testing of large populations.

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Subject:   Medical tests (diagnosis) Quantitative Research,  PCR (biochemistry) ,  COVID-19 (Disease)

Title: Shield Illinois Saliva Test

URL: https://www.uillinois.edu/shield/

Collection: COVID-19 Response at the University of Illinois

Description: Website for the SHEILD Illinois program, the University of Illinois System's initiative to make our innovative covidSHIELD saliva-based COVID-19 test available to K-12 schools, colleges and universities, companies and the public across the state of Illinois.

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Subject:   COVID-19 (Disease) Medical tests (Diagnosis),  PCR (biochemistry) ,  Pandemics

Page 1 of 1 (4 Total Results)